Keywords
autoimmune thrombocytopenic purpura
autoimmune hemolytic anemia
autoinmune neutropenia
How to Cite
Abstract
Introduction: Autoimmune cytopenias can occur in isolation or secondary to other pathologies, especially autoimmune systemic diseases. They can precede, present at the beginning or years after the debut of the associated disease. Objective: To determine the most frequent autoimmune cytopenias, the associated pathologies, the treatment and the evolution, in a group of patients from a third level hospital. Material and method: Retrospective, observational and descriptive study, of cross section, of clinical records of adult patients with the diagnosis of cytopenias of autoimmune origin, of the Department of Internal Medicine of the National Hospital of Itaugua, in the period between January 2012 and December 2017. Results: 45 patients were studied, with a M:H ratio of 3:1, mean age 44.2 ± 16 years. We found 29/45 patients with immune thrombocytopenic purpura (IT P), 12/45 cases of autoimmune hemolytic anemia (AHA), 2 patients with neutropenia and 2 cases with pancytopenia. The most frequent associated pathology corresponded to systemic lupus erythematosus (SLE): 12 patients (7 with IT P, 5 with AHA). The most commonly used medications were corticoids and IVIG, and to a lesser extent, Rituximab. Splenectomy was performed in only one case by relapsed IT P. Conclusion: The most frequent autoimmune cytopenia found in this group of patients was IT P, followed by autoimmune hemolytic anemia. The majority of cases responded to treatment with corticosteroids. It is important to recognize them to optimize treatment and follow-up.References
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