Autoimmune polyglandular syndrome type 3: comprehensive approach in the management of a multisystem autoimmune disease.
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Keywords

thyroiditis
vitiligo
therapeutic approach

How to Cite

1.
Hernández JA, Therán JS, Gómez JA, Dulcey LA. Autoimmune polyglandular syndrome type 3: comprehensive approach in the management of a multisystem autoimmune disease. Rev. parag. reumatol. [Internet]. 2025 Dec. 30 [cited 2026 Feb. 23];11(2):87-90. Available from: https://revista.spr.org.py/index.php/spr/article/view/226

Abstract

Autoimmune Polyendocrine Syndrome (APS) type 3 is a multisystem disorder characterized by the coexistence of multiple autoimmune conditions, including Hashimoto's thyroiditis, vitiligo, and celiac disease. This syndrome predominantly affects women, with a strong genetic predisposition associated with HLA haplotypes. Diagnosis requires the identification of at least two concurrent autoimmune diseases through detailed clinical history, laboratory testing, and specific diagnostic criteria. The therapeutic approach involves targeted interventions for each condition. Multidisciplinary collaboration and patient education are essential to improving quality of life, emphasizing the importance of early diagnosis and a personalized management strategy.

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References

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This work is licensed under a Creative Commons Attribution 4.0 International License.

Copyright (c) 2025 Jorge Andrés Hernández, Juan Sebastián Therán, Jaime Alberto Gómez, Luis Andrés Dulcey

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