Lupus nephritis is a frequent cause of secondary nephropathy in Paraguay

  • Alex Chamorro León Universidad Nacional de Asunción, Facultad de Ciencias Médicas, Hospital de Clínicas, Departamento de Nefrología, San Lorenzo, Paraguay https://orcid.org/0000-0002-6832-295X
  • Lourdes Carolina Vázquez Jiménez Universidad Nacional de Asunción. Facultad de Ciencias Médicas. Departamento de Nefrología. https://orcid.org/0000-0003-1416-552X
  • Lilian Michele Brítez González Universidad Nacional de Asunción, Facultad de Ciencias Médicas, Hospital de Clínicas, Departamento de Nefrología, San Lorenzo, Paraguay https://orcid.org/0000-0003-2094-8985
  • Marcelo Ramón Barrios Gini Universidad Nacional de Asunción, Facultad de Ciencias Médicas, Hospital de Clínicas, Departamento de Nefrología, San Lorenzo, Paraguay https://orcid.org/0000-0001-8853-4653
  • Idalina de Jesús Stanley Universidad Nacional de Asunción, Facultad de Ciencias Médicas, Hospital de Clínicas, Departamento de Nefrología, San Lorenzo, Paraguay https://orcid.org/0000-0003-4928-3585
DOI: https://doi.org/10.18004/rpr/2022.08.01.16
Keywords: Glomerulonephritis, Lupus nephritis, Kidney biopsy

Abstract

Introduction: Lupus Nephritis (LN) is a poor prognostic factor in patients with Systemic Lupus Erythematosus (SLE). Ultrasound-guided renal biopsy is performed to classify LN. General Objective: To identify the most frequently biopsied classes of LN at the Hospital de Clínicas FCM-UNA.

Specific Objectives: To recognize the clinical presentation in patients with LN and the clinical-pathological correlation of LN in the Hospital de Clínicas. To determine the most frequent clinical indication for biopsy. To know the most frequent technical complications of the procedure.

Methods: We conducted a retrospective, observational, descriptive, cross-sectional study design.

Results: LN was the most frequent (89%, 33/37) cause of secondary glomerulopathy in biopsies. Clinical indications for renal biopsy in LN were proteinuria with a diagnosis of SLE (85%), nephrotic syndrome (6%), nephritic syndrome (6%), and isolated proteinuria (3%). The pathological LN classes found were: 64% class IV-G, 18% class IV-S, 12% class V, 6% class III. Regarding complications, 3% developed minimal perirenal hematoma.

Conclusion: LN class IV-G was the predominant biopsy class in our patients. The most frequent form of presentation was.

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Published
2022-06-04
How to Cite
1.
Chamorro León A, Vázquez Jiménez LC, Brítez González LM, Barrios Gini MR, Stanley I de J. Lupus nephritis is a frequent cause of secondary nephropathy in Paraguay. Rev. parag. reumatol. [Internet]. 2022Jun.4 [cited 2025Apr.2];8(1):16-0. Available from: http://revista.spr.org.py/index.php/spr/article/view/148
Issue
Vol 8 No 1 (2022): January-June
Section
ORIGINAL ARTICLES

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