Uso de metotrexato en la artritis reumatoide
Resumen
El objetivo del tratamiento de la artritis reumatoide es detener, o al menos retrasar, la inflamación y el daño articular. Los fármacos modificadores de la enfermedad constituyen la base fundamental del tratamiento de la Artritis Reumatoide. El uso correcto de los fármacos modificadores de la enfermedad ha mejorado el pronóstico de la AR, en función de su utilización precoz y fijación de un objetivo terapéutico concreto. El Metotrexato se considera el fármaco de anclaje del tratamiento, se recomienda como fármaco preferente al inicio de la enfermedad y en combinación con otros fármacos durante su evolución según actividad de la enfermedad. La revisión actual intenta orientar sobre el uso adecuado de este fármaco en artritis reumatoide: dosis inicial, vía de administración, incremento y disminución de dosis, seguimiento del paciente, uso de ácido fólico/folínico, situaciones especiales previas y durante el tratamiento.Descargas
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